The neurocognitive correlates of DTI indicators of white matter disorganization in pediatric moderate-to-severe traumatic brain injury
In the year following TBI, some pediatric patients experienced persisting working memory disturbance while others exhibited recovery; stratification was based on an event-related potential marker. More or less improvement in neurocognition was also associated with the degree of WM disorganization. IHTT, measured post-acutely after TBI, and progression of WM disorganization over time predicted neurocognitive trajectories at the chronic timeframe - potentially representing a prognostic biomarker.
Authors
- Kevin Bickart (ORCID: https://orcid.org/0000-0002-8389-8922)
- Aliyah Snyder (ORCID: https://orcid.org/0000-0003-1185-7424)
- Meeryo Choe (ORCID: https://orcid.org/0000-0001-8142-9471)
- Emily L. Dennis (ORCID: https://orcid.org/0000-0001-7112-4009)
- Christopher C. Giza (ORCID: https://orcid.org/0000-0002-5721-2667)
- Robert F. Asarnow (ORCID: https://orcid.org/0000-0002-4994-9642)
- Daniel Andre Ignacio (ORCID: https://orcid.org/0000-0002-1045-8328)
- Talin Babikian (ORCID: https://orcid.org/0000-0002-2270-8566)
- Anne M. Brown (ORCID: https://orcid.org/0000-0001-6951-8228)
Institutions
- University of California, Los Angeles (US)
- University of Utah (US)
- University of Florida Health (US)
- Mattel Children's Hospital (US)
Publication Details
- Journal
- Frontiers in Human Neuroscience
- Published
- 2024-10-31
- DOI
- https://doi.org/10.3389/fnhum.2024.1470710
- Citations
- 5
- Primary Topic
- Traumatic Brain Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 1.93
Funders
- National Institute of Child Health and Human Development