Increased levels of antibodies to synaptopodin and annexin 1 in patients with primary podocytopathies

Levels of antibodies targeting synaptopodin and annexin 1 were notably elevated in patients diagnosed with MCD and FSGS compared to those with MN and healthy controls. A panel comprising both antibodies demonstrated moderate to high sensitivity and specificity for diagnosis MCD or FSGS.

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Publication Details

Journal
Frontiers in Nephrology
Published
2024-10-31
DOI
https://doi.org/10.3389/fneph.2024.1471078
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
Field-Weighted Citation Impact
0.00

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article

Increased levels of antibodies to synaptopodin and annexin 1 in patients with primary podocytopathies

Sergey Moiseev, А. С. Кононихин, И. И. Алентов, Е. Н. Николаев et al.
Frontiers in Nephrology
Renal Diseases and Glomerulopathies
article

Increased levels of antibodies to synaptopodin and annexin 1 in patients with primary podocytopathies

Sergey Moiseev, А. С. Кононихин, И. И. Алентов, Е. Н. Николаев, Natalia Chebotareva, Н. С. Сергеева, Anatoliy Vinogradov, Evgenia A. Biryukova, Evgeniya A. Charionovskaya
article en

Abstract

Levels of antibodies targeting synaptopodin and annexin 1 were notably elevated in patients diagnosed with MCD and FSGS compared to those with MN and healthy controls. A panel comprising both antibodies demonstrated moderate to high sensitivity and specificity for diagnosis MCD or FSGS.

Frontiers in NephrologyVol. 4
Skolkovo Institute of Science and Technology (RU), Sechenov University (RU), Lomonosov Moscow State University (RU), P.A. Hertzen Moscow Oncology Research Institute (RU)
Russian Science Support Foundation, Russian Science Foundation
Good health and well-being
Openalex Percentile: Top 71%
Renal Diseases and Glomerulopathies
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