PYGL regulation of glycolysis and apoptosis in glioma cells under hypoxic conditions via HIF1α-dependent mechanisms
<i>PYGL</i> is a crucial regulator of glycolysis in gliomas and contributes to tumor progression under hypoxic conditions. Targeting <i>PYGL</i> and its associated metabolic pathways may offer new therapeutic strategies for glioma treatment.
Authors
- Jinchun Wang (ORCID: https://orcid.org/0000-0001-6174-5872)
- Tingyu Cao
Institutions
- Shaoxing University (CN)
- Tianjin Medical University General Hospital (CN)
- Shaoxing People's Hospital (CN)
Publication Details
- Journal
- Translational Cancer Research
- Published
- 2024-10-01
- DOI
- https://doi.org/10.21037/tcr-24-1974
- Citations
- 4
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 1.14