Identification and validation of a novel innate lymphoid cell-based signature to predict prognosis and immune response in liver cancer by integrated single-cell RNA analysis and bulk RNA sequencing

A novel prognostic feature of ILC potentially involved in HCC was discovered. It showed high values in predicting patient overall survival (OS) as well as good differences in immunity and drug sensitivity. Therefore, targeting these ILC signatures may be a potential effective approach in HCC treatment.

Authors

Xiaolong Yuan (ORCID: https://orcid.org/0000-0002-3743-0130)
Jiakuan Peng
Meng Pan (ORCID: https://orcid.org/0000-0002-4380-2324)
Ruiqi Wu (ORCID: https://orcid.org/0000-0001-8020-0827)
Xiaopeng Chen (ORCID: https://orcid.org/0000-0002-4551-0165)

Institutions

Wannan Medical College (CN)
First Affiliated Hospital of Wannan Medical College (CN)

Publication Details

Journal: Translational Cancer Research
Published: 2024-10-01
DOI: https://doi.org/10.21037/tcr-24-725
Citations: 1
Primary Topic: Cancer Immunotherapy and Biomarkers
Type: article
Field-Weighted Citation Impact: 0.28

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article

Identification and validation of a novel innate lymphoid cell-based signature to predict prognosis and immune response in liver cancer by integrated single-cell RNA analysis and bulk RNA sequencing

Xiaolong Yuan, Jiakuan Peng, Meng Pan, Ruiqi Wu et al.

Oct 1, 2024

1 citations

Translational Cancer Research

Cancer Immunotherapy and Biomarkers

0.28

article

Identification and validation of a novel innate lymphoid cell-based signature to predict prognosis and immune response in liver cancer by integrated single-cell RNA analysis and bulk RNA sequencing

Xiaolong Yuan, Jiakuan Peng, Meng Pan, Ruiqi Wu, Xiaopeng Chen

October 1, 2024article en

1 citations

Abstract

A novel prognostic feature of ILC potentially involved in HCC was discovered. It showed high values in predicting patient overall survival (OS) as well as good differences in immunity and drug sensitivity. Therefore, targeting these ILC signatures may be a potential effective approach in HCC treatment.

Translational Cancer ResearchVol. 13(10)

Wannan Medical College (CN), First Affiliated Hospital of Wannan Medical College (CN)

Good health and well-being

Openalex Percentile: Top 34%

Cancer Immunotherapy and Biomarkers

0.28

DOI Open Access PDF OpenAlex

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Identification and validation of a novel innate lymphoid cell-based signature to predict prognosis and immune response in liver cancer by integrated single-cell RNA analysis and bulk RNA sequencing — Xiaolong Yuan, Jiakuan Peng, et al. · Translational Cancer Research (2024) | TGRS Research Map | TGRS