Evidence for stability of cardiac troponin T concentrations measured with a high sensitivity TnT test in serum and lithium heparin plasma after six-year storage at −80 °C and multiple freeze-thaw cycles
Over 6 years of storage at -80 °C, recovery of hs-cTnT in serum and heparin plasma was similar and within common lot-to-lot variation. Yet, when evaluating absolute delta increments around hs-cTnT clinical decision points, long-term stored sera displayed better clinical performance compared to heparin plasma samples.
Authors
- Christa M. Cobbaert (ORCID: https://orcid.org/0000-0003-3565-1404)
- Linda M. Henricks (ORCID: https://orcid.org/0000-0003-0141-7927)
- Fred P.H.T.M. Romijn (ORCID: https://orcid.org/0000-0003-4470-7959)
Institutions
- Leiden University Medical Center (NL)
- Amsterdam University Medical Centers (NL)
Publication Details
- Journal
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1515/cclm-2024-0787
- Citations
- 5
- Primary Topic
- Acute Myocardial Infarction Research
- Type
- article
- Field-Weighted Citation Impact
- 2.01
Funders
- Roche Diagnostics