Interrupted Michael Reaction: Sulfophosphinoylation of α,β-Unsaturated Ketones Catalyzed by Phosphine
An efficient method for phosphine-catalyzed sulfophosphinoylation of α,β-unsaturated ketones for synthesis allylic organophosphorus compounds has been reported, in which α,β-unsaturated compounds acting as zwitterions react with electrophiles and nucleophiles to form a C-P bond and a C-O bond and obtain allylic organophosphorus with high regio- and stereoselectivity in moderate to excellent yields.
Authors
- Ya-Wen Xue
- Xiaohong Wei (ORCID: https://orcid.org/0000-0002-5680-9509)
- Yanbin Wang (ORCID: https://orcid.org/0000-0001-5716-3183)
- Qiong Su (ORCID: https://orcid.org/0000-0001-9146-4983)
- Xiaohong Wang
- Xuan Liu (ORCID: https://orcid.org/0009-0004-3094-2389)
Institutions
- State Ethnic Affairs Commission (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1021/acs.joc.4c01860
- Citations
- 1
- Primary Topic
- Organophosphorus compounds synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.25
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Gansu Province
- Fundamental Research Funds for the Central Universities