The clinical efficacy of cGMP-specific sildenafil on mitochondrial biogenesis induction and renal damage in cats with acute on chronic kidney disease
While sildenafil citrate has been determined to induce a low level of MB and to have a beneficial effect on glomerular filtration, it is observed to be ineffective in mitigating renal damage and fibrosis via the TGF-β/SMAD pathway in cats with ACKD.
Authors
- Bengü Bilgiç (ORCID: https://orcid.org/0000-0002-6952-2937)
- Merve İder (ORCID: https://orcid.org/0000-0003-2928-5452)
- Semih İZMİRLİ (ORCID: https://orcid.org/0000-0002-1781-0494)
- Mehmet Erman Or (ORCID: https://orcid.org/0000-0002-8764-1956)
- Erdem Gülersoy (ORCID: https://orcid.org/0000-0001-8511-0150)
- Murat Kaan Durgut (ORCID: https://orcid.org/0000-0002-4582-8536)
- Merve Cansu KILIÇKAYA (ORCID: https://orcid.org/0000-0002-7130-6555)
- Deniz Zeynep TELCİ (ORCID: https://orcid.org/0000-0001-6825-2093)
- Banu Dokuzeylül (ORCID: https://orcid.org/0000-0003-3086-4726)
- Süleyman Serhat İyigün (ORCID: https://orcid.org/0000-0002-3270-1931)
- Mehmet Maden (ORCID: https://orcid.org/0000-0003-2954-6763)
- Amir Naseri (ORCID: https://orcid.org/0000-0001-9140-5879)
Institutions
- Selçuk University (TR)
- Istanbul University-Cerrahpaşa (TR)
- Harran University (TR)
Publication Details
- Journal
- BMC Veterinary Research
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1186/s12917-024-04345-9
- Citations
- 1
- Primary Topic
- Electrolyte and hormonal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.42
Funders
- Türkiye Bilimsel ve Teknolojik Araştırma Kurumu
- Selçuk Üniversitesi