Older Adults with Ph Negative Acute Lymphoblastic Leukemia: a Monocentric Experience on Consecutive Patients Aged More than 55 years

Background: Treating with curative intent elderly patients affected by acute lymphoblastic leukemia (ALL) is an unmet clinical need. Comorbidities, lower tolerance to organ toxicities, and poor disease-related prognostic features make it difficult to cure these patients. Objectives: To analyze the outcome of ALL elderly patients aged over 55 years treated intensively or with the best supportive care (BSC) over the last 20 years.

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Publication Details

Journal
Mediterranean Journal of Hematology and Infectious Diseases
Published
2024-10-31
DOI
https://doi.org/10.4084/mjhid.2024.080
Primary Topic
Acute Lymphoblastic Leukemia research
Type
article
Field-Weighted Citation Impact
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article

Older Adults with Ph Negative Acute Lymphoblastic Leukemia: a Monocentric Experience on Consecutive Patients Aged More than 55 years

Francesca Federico, Marco Chiarini, Erika Borlenghi, Mariella Tonelli et al.
Mediterranean Journal of Hematology and Infectious Diseases
Acute Lymphoblastic Leukemia research
article

Older Adults with Ph Negative Acute Lymphoblastic Leukemia: a Monocentric Experience on Consecutive Patients Aged More than 55 years

Francesca Federico, Marco Chiarini, Erika Borlenghi, Mariella Tonelli, Diego Bertoli, Michele Malagola, Lorenzo Masina, Chiara M. Cattaneo, Carlotta Giupponi, Tatiana Zollner, Chiara Pagani, Alessandra Tucci, Angela Passi, Rossella Leopaldo, Giuseppe Rossi, Alessandra Sottini
article en

Abstract

Background: Treating with curative intent elderly patients affected by acute lymphoblastic leukemia (ALL) is an unmet clinical need. Comorbidities, lower tolerance to organ toxicities, and poor disease-related prognostic features make it difficult to cure these patients. Objectives: To analyze the outcome of ALL elderly patients aged over 55 years treated intensively or with the best supportive care (BSC) over the last 20 years.

Mediterranean Journal of Hematology and Infectious DiseasesVol. 16(1)
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT), University of Brescia (IT)
No poverty
Openalex Percentile: Top 70%
Acute Lymphoblastic Leukemia research
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