Interleukin-6, C-Reactive Protein, and Recurrence After Stroke: A Time-Course Analysis of Individual-Participant Data
Timing of sample measurement after stroke modifies the association with recurrent major adverse cardiovascular events for IL-6 but not hsCRP. These data inform future randomized controlled trial designs incorporating biomarker-based selection of patients for anti-inflammatory therapies.
Authors
- Mikel Vicente‐Pascual (ORCID: https://orcid.org/0000-0002-5445-7853)
- Linxin Li (ORCID: https://orcid.org/0000-0002-3636-8355)
- Peter M. Rothwell (ORCID: https://orcid.org/0000-0001-9739-9211)
- Nobukazu Miyamoto (ORCID: https://orcid.org/0000-0003-3037-169X)
- John McCabe (ORCID: https://orcid.org/0000-0003-2029-1303)
- Sarah Gorey (ORCID: https://orcid.org/0000-0001-8079-7969)
- Cathal Walsh (ORCID: https://orcid.org/0000-0001-6599-9562)
- Mira Katan (ORCID: https://orcid.org/0000-0002-9265-8066)
- Yuji Ueno (ORCID: https://orcid.org/0000-0002-8617-3695)
- Mark Woodward (ORCID: https://orcid.org/0000-0001-9800-5296)
- Katie Harris (ORCID: https://orcid.org/0000-0003-2444-2869)
- Joan Montaner (ORCID: https://orcid.org/0000-0003-4845-2279)
- Pablo Hervella (ORCID: https://orcid.org/0000-0003-1249-6333)
- William Whiteley (ORCID: https://orcid.org/0000-0002-4816-8991)
- Christina Jern (ORCID: https://orcid.org/0000-0002-7531-2354)
- Peter J. Kelly (ORCID: https://orcid.org/0000-0003-4772-6565)
- Gian Marco De Marchis (ORCID: https://orcid.org/0000-0002-0342-9780)
- Ramón Iglesias‐Rey (ORCID: https://orcid.org/0000-0002-9985-9135)
- Cathie Sudlow (ORCID: https://orcid.org/0000-0002-7725-7520)
- Francisco Purroy (ORCID: https://orcid.org/0000-0002-1808-5968)
- Markus Arnold (ORCID: https://orcid.org/0000-0002-5524-2301)
- Tara M. Stanne (ORCID: https://orcid.org/0000-0001-9668-0407)
Institutions
- University College Dublin (IE)
- Universitat Autònoma de Barcelona (ES)
- Universitat de Lleida (ES)
- The George Institute for Global Health (GB)
- Trinity College Dublin (IE)
- Sahlgrenska University Hospital (SE)
- Hospital Universitari Arnau de Vilanova (ES)
- University Hospital of Basel (CH)
- Stroke Association (GB)
- Mater Misericordiae University Hospital (IE)
- Juntendo University (JP)
- University of Oxford (GB)
- Health Research Board (IE)
- Hospital Universitario Virgen Macarena (ES)
- University Hospital of Zurich (CH)
- Vall d'Hebron Institut de Recerca (ES)
- MRC Centre for Regenerative Medicine (GB)
- Nuffield Health (GB)
- The George Institute for Global Health (AU)
- Vall d'Hebron Hospital Universitari (ES)
- Instituto de Biomedicina de Sevilla (ES)
- Instituto de Investigación Sanitaria de Santiago (ES)
- Institute for Medical Informatics and Biostatistics (CH)
- University of Gothenburg (SE)
- University of Edinburgh (GB)
Publication Details
- Journal
- Stroke
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1161/strokeaha.124.047820
- Citations
- 16
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 3.96