Circular RNA landscape in extracellular vesicles from human biofluids
This study unveils the extensive repertoire of EV-circRNAs across human biofluids, offering insights into their potential as disease biomarkers and their mechanistic roles within EVs. The identification of specific circRNAs and the elucidation of RBP-mediated sorting mechanisms open new avenues for the clinical application of EV-circRNAs in disease diagnostics and therapeutics.
Authors
- Hena Zhang
- Zhi Fang (ORCID: https://orcid.org/0000-0001-5002-4842)
- Jingjing Zhao (ORCID: https://orcid.org/0000-0002-9880-508X)
- Qiaojuan Li
- Shenglin Huang (ORCID: https://orcid.org/0000-0003-1279-0794)
- Yan Shen (ORCID: https://orcid.org/0000-0002-7883-5169)
- Hongyan Lai (ORCID: https://orcid.org/0009-0007-9417-0113)
- Qin Li (ORCID: https://orcid.org/0000-0002-3907-3245)
- Yan Li (ORCID: https://orcid.org/0000-0002-9343-5278)
- Jia Hu (ORCID: https://orcid.org/0000-0003-2618-2079)
- Hongwu Yu
Institutions
- Fujian Medical University (CN)
- Shanghai Medical College of Fudan University (CN)
- Fudan University (CN)
- Fudan University Shanghai Cancer Center (CN)
- Fujian Provincial Hospital (CN)
- Fujian Provincial Cancer Hospital (CN)
Publication Details
- Journal
- Genome Medicine
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1186/s13073-024-01400-w
- Citations
- 19
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 4.44
Funders
- National Natural Science Foundation of China