Integrated Metabolomics and Network Pharmacology Study on the Mechanism of Rehmanniae radix Extract for Treating Thrombosis
This study confirmed the antithrombotic effect of high-dose RR, revealed the antithrombotic mechanism and potential material basis, and laid the foundation for the antithrombotic clinical application of RR. Furthermore, it provides a successful case reference for screening natural herbal components and exploring their potential pharmacological mechanisms.
Authors
- Kezhu Yuan
- Mingquan Wu (ORCID: https://orcid.org/0000-0003-4145-9531)
- Shunjie Zhang (ORCID: https://orcid.org/0000-0002-5407-1424)
- Hongling Du (ORCID: https://orcid.org/0000-0003-0923-7592)
- Zhirui Yang (ORCID: https://orcid.org/0009-0004-1017-4677)
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Fourth People's Hospital of Sichuan Province (CN)
- Chengdu Second People's Hospital (CN)
- Public Health Clinical Center of Chengdu (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Drug Design Development and Therapy
- Published
- 2024-10-01
- DOI
- https://doi.org/10.2147/dddt.s475838
- Citations
- 3
- Primary Topic
- Phytochemistry and Biological Activities
- Type
- article
- Field-Weighted Citation Impact
- 1.80