Sequencing the orthologs of human autosomal forensic short tandem repeats provides individual- and species-level identification in African great apes

Orthologs of most human aSTRs in the ForenSeq DNA Signature Prep Kit can be analysed in African great apes. Primer redesign would reduce observed variability in amplification across some loci. MPS of the orthologs of human loci provides better resolution for both individual and (sub)species identification in great apes than standard CE-based approaches, and has the further advantage that there is no need to limit the number and size ranges of analysed loci.

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Journal
BMC Ecology and Evolution
Published
2024-10-31
DOI
https://doi.org/10.1186/s12862-024-02324-0
Primary Topic
Genomics and Phylogenetic Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Sequencing the orthologs of human autosomal forensic short tandem repeats provides individual- and species-level identification in African great apes

Jon H. Wetton, Ettore Fedele, Mark A. Jobling
BMC Ecology and Evolution
Genomics and Phylogenetic Studies
article

Sequencing the orthologs of human autosomal forensic short tandem repeats provides individual- and species-level identification in African great apes

Jon H. Wetton, Ettore Fedele, Mark A. Jobling
article en

Abstract

Orthologs of most human aSTRs in the ForenSeq DNA Signature Prep Kit can be analysed in African great apes. Primer redesign would reduce observed variability in amplification across some loci. MPS of the orthologs of human loci provides better resolution for both individual and (sub)species identification in great apes than standard CE-based approaches, and has the further advantage that there is no need to limit the number and size ranges of analysed loci.

BMC Ecology and EvolutionVol. 24(1)
University of Leicester (GB), Genomics (United Kingdom) (GB)
University of Leicester, Natural Environment Research Council
Life in Land
Openalex Percentile: Top 83%
Genomics and Phylogenetic Studies
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Sequencing the orthologs of human autosomal forensic short tandem repeats provides individual- and species-level identification in African great apes — Jon H. Wetton, Ettore Fedele, et al. · BMC Ecology and Evolution (2024) | TGRS Research Map | TGRS