Evaluating serum periostin and YKL-40 as biomarkers for airway remodeling and hyperresponsiveness in pediatric asthma
Periostin is linked to atopic asthma and correlates with exercise-induced bronchoconstriction, FeNO, and eosinophil counts, highlighting its role in Th2 inflammation. YKL-40 is a general asthma marker, indicating airway remodeling. These findings suggest that targeting these markers can improve personalized treatment strategies for pediatric asthma.
Authors
- Hey‐Sung Baek (ORCID: https://orcid.org/0000-0003-0297-9446)
- Man Yong Han (ORCID: https://orcid.org/0000-0002-9077-5779)
- Il Tae Hwang (ORCID: https://orcid.org/0000-0002-3885-4322)
- You‐Jung Choi (ORCID: https://orcid.org/0000-0003-3512-855X)
- Su Ji Kim
Institutions
- Hallym University (KR)
- CHA University Bundang Medical Center (KR)
- Kangdong Sacred Heart Hospital (KR)
- CHA University (KR)
Publication Details
- Journal
- World Allergy Organization Journal
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1016/j.waojou.2024.100991
- Citations
- 1
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.33