Plasmapheresis as an Ischaemic Stroke Treatment: A Rare Case of Acquired Thrombotic Thrombocytopenic Purpura

Acquired thrombotic thrombocytopenic purpura (acquired TTP) is a rare clinical syndrome caused by a decreased ADAMST13 activity, leading to systemic microvascular thrombotic events, with high mortality rates when the diagnosis and treatment are delayed. The authors report an acquired TTP in a patient with cerebrovascular disease. The aim is to emphasize the importance of considering atypical acquired TTP clinical presentations in order to optimize diagnostic and treatment approaches, minimize possible sequels, and improve the prognosis.

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Journal
Cureus
Published
2024-10-31
DOI
https://doi.org/10.7759/cureus.72762
Primary Topic
Complement system in diseases
Type
article
Field-Weighted Citation Impact
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article

Plasmapheresis as an Ischaemic Stroke Treatment: A Rare Case of Acquired Thrombotic Thrombocytopenic Purpura

Sofia Nóbrega, Francisco Cândido Cardoso Barreto, Rui Fernandes, Carolina Carvalhinha et al.
Cureus
Complement system in diseases
article

Plasmapheresis as an Ischaemic Stroke Treatment: A Rare Case of Acquired Thrombotic Thrombocytopenic Purpura

Sofia Nóbrega, Francisco Cândido Cardoso Barreto, Rui Fernandes, Carolina Carvalhinha, Teresa Faria
article en

Abstract

Acquired thrombotic thrombocytopenic purpura (acquired TTP) is a rare clinical syndrome caused by a decreased ADAMST13 activity, leading to systemic microvascular thrombotic events, with high mortality rates when the diagnosis and treatment are delayed. The authors report an acquired TTP in a patient with cerebrovascular disease. The aim is to emphasize the importance of considering atypical acquired TTP clinical presentations in order to optimize diagnostic and treatment approaches, minimize possible sequels, and improve the prognosis.

CureusVol. 16(10)
Hospital Dr. Nélio Mendonça (PT)
Good health and well-being
Openalex Percentile: Top 75%
Complement system in diseases
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