Sex differences in contextual fear conditioning and extinction after acute and chronic nicotine treatment
Despite the similar impacts of nicotine withdrawal on gene expression levels, fosb, cfos, bdnf and erbb4 levels in the ventral hippocampus were predictive of delays in female extinction learning alone. This suggests sex specific dysfunction in hippocampal circuitry may contribute to female specific nicotine withdrawal induced deficits in extinction learning.
Authors
- Jack Keady
- Kristen A. McLaurin (ORCID: https://orcid.org/0000-0001-7816-1806)
- Jill Turner (ORCID: https://orcid.org/0000-0002-7258-1639)
- Judy C. Songrady
- Marissa C. Hessing
Institutions
- University of Kentucky (US)
Publication Details
- Journal
- Biology of Sex Differences
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1186/s13293-024-00656-6
- Citations
- 7
- Primary Topic
- Nicotinic Acetylcholine Receptors Study
- Type
- article
- Field-Weighted Citation Impact
- 1.64
Funders
- National Institutes of Health