Outcomes and inflammation changes in different types of immunocompromised patients with critically ill COVID-19 admitted to ICU: a national multicenter study
Critically ill COVID-19 patients admitted to the ICU exhibit distinct clinical outcomes based on their immunosuppression status, with cancer patients facing the highest mortality rate due to variations in inflammatory responses linked to their immunosuppression mechanisms. Monitoring dynamic changes in inflammatory markers and immune cells, particularly CD8<sup>+</sup> T lymphocytes and IL-6, may offer valuable prognostic insights for these patients.
Authors
- Qingyuan Zhan (ORCID: https://orcid.org/0000-0003-0021-0270)
- Hangyong He (ORCID: https://orcid.org/0000-0001-9972-0929)
- Xiaojing Wu (ORCID: https://orcid.org/0000-0002-0590-7627)
- Linna Huang (ORCID: https://orcid.org/0000-0002-5682-8814)
- Ziying Chen (ORCID: https://orcid.org/0009-0005-8931-6662)
- Yuqiong Wang (ORCID: https://orcid.org/0000-0002-4112-4558)
- Chunyan Li
- Ying Cai (ORCID: https://orcid.org/0000-0003-4105-5916)
- Tianshu Zhai
- Qi Zhang (ORCID: https://orcid.org/0000-0003-1249-9884)
Institutions
- Nanchang University (CN)
- Harbin Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking University (CN)
- China-Japan Friendship Hospital (CN)
- Second Affiliated Hospital of Harbin Medical University (CN)
- First Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- BMC Pulmonary Medicine
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1186/s12890-024-03362-6
- Citations
- 3
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- Key Research and Development Program of Jiangxi Province
- China-Japan Friendship Hospital