Endoscopic morphology of gastric MALT lymphoma correlate with API2/MALT1 fusion and predict treatment response after helicobacter pylori eradication
Gastric MALT lymphomas with superficial-type morphology, particularly those with defined borders resembling early gastric cancer, were associated with API2/MALT1 fusion and a lower remission rate after Hp eradication therapy. This suggests that endoscopic morphology, along with API2/MALT1 fusion status, could help predict the therapeutic response, with API2/MALT1 fusion serving as a critical indicator of treatment resistance.
Authors
- Jinlin Yang (ORCID: https://orcid.org/0000-0001-8726-7258)
- Hailin Yan
- Xianyang Luo
- Yuqiang Liu (ORCID: https://orcid.org/0000-0002-0350-3071)
- Bing-Can Yang
- Zhu Wang
Institutions
- Xiamen University (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
- Zhongshan Hospital of Xiamen University (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1186/s12876-024-03476-5
- Citations
- 1
- Primary Topic
- Helicobacter pylori-related gastroenterology studies
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- Key Technologies Research and Development Program
- National Key Research and Development Program of China