A Randomized Trial of Drug Route in Out-of-Hospital Cardiac Arrest
Among adults with out-of-hospital cardiac arrest requiring drug therapy, the use of an intraosseous-first vascular access strategy did not result in higher 30-day survival than an intravenous-first strategy. (Funded by the National Institute for Health and Care Research; PARAMEDIC-3 ISRCTN Registry number, ISRCTN14223494.).
Authors
- Adam T. Wright (ORCID: https://orcid.org/0000-0001-6844-145X)
- Matthew Limmer
- Julia Williams (ORCID: https://orcid.org/0000-0003-0796-5465)
- Keith Couper (ORCID: https://orcid.org/0000-0003-2123-2022)
- Henry Nwankwo (ORCID: https://orcid.org/0000-0001-7401-1923)
- Robert Spaight (ORCID: https://orcid.org/0000-0003-4361-5876)
- Emma Burrow
- Gemma Bradley (ORCID: https://orcid.org/0000-0002-0031-964X)
- Tom Quinn (ORCID: https://orcid.org/0000-0002-5116-0034)
- Garry Squires (ORCID: https://orcid.org/0000-0003-2105-3358)
- James Mason (ORCID: https://orcid.org/0000-0001-9210-4082)
- Anne‐Marie Slowther (ORCID: https://orcid.org/0000-0002-3338-8457)
- Felix Michelet (ORCID: https://orcid.org/0009-0003-6903-7637)
- Michael A. Smyth (ORCID: https://orcid.org/0000-0003-0220-2223)
- Shona Brown
- Justin Kearney (ORCID: https://orcid.org/0009-0004-6202-6457)
- S. Wiltshire
- Jason A. Wiles (ORCID: https://orcid.org/0000-0001-7402-6914)
- Ranjit Lall (ORCID: https://orcid.org/0000-0003-1737-2866)
- Nigel Lang (ORCID: https://orcid.org/0000-0001-7044-3489)
- Ria Osborne
- Theresa Foster (ORCID: https://orcid.org/0000-0002-6395-0885)
- Steve Bell (ORCID: https://orcid.org/0000-0003-3891-6623)
- Martina Brown (ORCID: https://orcid.org/0000-0003-3083-8958)
- Josh Miller (ORCID: https://orcid.org/0000-0003-1990-4029)
- Gregory Adam Whitley (ORCID: https://orcid.org/0000-0003-2586-6815)
- M. S. Waddington
- C. V. Evans (ORCID: https://orcid.org/0000-0002-8813-5748)
- Belinda Tibbetts
- Sara Wood
- Chen Ji (ORCID: https://orcid.org/0000-0003-4919-3299)
- Rachael Fothergill (ORCID: https://orcid.org/0000-0003-1341-6200)
- Gavin D. Perkins (ORCID: https://orcid.org/0000-0003-3027-7548)
- Karl Charlton (ORCID: https://orcid.org/0000-0002-9601-1083)
- Chloe Norman (ORCID: https://orcid.org/0000-0002-3275-3141)
- Kath Starr (ORCID: https://orcid.org/0000-0003-3356-7751)
- Alison Walker (ORCID: https://orcid.org/0000-0002-2232-9734)
- Jerry P. Nolan (ORCID: https://orcid.org/0000-0003-3141-3812)
- Nigel Rees (ORCID: https://orcid.org/0000-0001-8799-5335)
- Victoria L Dra'gon
- Adam Smith (ORCID: https://orcid.org/0000-0002-6157-8979)
- Carla Mills
- Charles D. Deakin
- John Long (ORCID: https://orcid.org/0009-0003-9384-5386)
- J Falloon
- Andrew Claxton Dip
Institutions
- University Hospital Coventry (GB)
Publication Details
- Journal
- New England Journal of Medicine
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1056/nejmoa2407780
- Citations
- 65
- Primary Topic
- Cardiac Arrest and Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 44.91
Funders
- Health and Care Research Wales
- National Institute for Health and Care Research
- British Heart Foundation
- Department of Health and Social Care
- Health Technology Assessment Programme