Andrographis paniculata improves glucose regulation by enhancing insulin sensitivity and upregulating GLUT 4 expression in Wistar rats
<i>A. paniculata</i> exerts positive effect on glucose metabolism and utilization by improving insulin sensitivity and upregulating the activities of glycolytic enzymes and GLUT 4 protein expression. This implies that <i>A. paniculata</i> may be beneficial in preventing insulin resistance and incident diabetes. Nonetheless, it should be used with caution to prevent hypoglycaemia in a non-diabetic state.
Authors
- O. O. Oladipo
- Roland Eghoghosoa Akhigbe (ORCID: https://orcid.org/0000-0002-3874-5927)
- W A Saka (ORCID: https://orcid.org/0000-0002-3153-3657)
- Tunmise Maryanne Akhigbe (ORCID: https://orcid.org/0000-0002-8762-3395)
- Adedayo T. Adekola
- Ayomide Isaac Omole
- Olubunmi Simeon Oyekunle
- M.B. Ajayi
Institutions
- Osun State University (NG)
- Ladoke Akintola University of Technology (NG)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2024-10-31
- DOI
- https://doi.org/10.3389/fnut.2024.1416641
- Citations
- 8
- Primary Topic
- Andrographolide Research and Applications
- Type
- article
- Field-Weighted Citation Impact
- 5.73