Efficacy and Mechanism of Schisandra chinensis Fructus Water Extract in Alzheimer’s Disease: Insights from Network Pharmacology and Validation in an Amyloid-β Infused Animal Model
SCF could be a potential AD therapeutic agent by activating the parasympathetic nervous system to reduce hippocampal oxidative stress and inflammation, warranting further clinical investigations of its efficacy.
Authors
- Haeng Jeon Hur (ORCID: https://orcid.org/0000-0001-9469-010X)
- Du‐Jeon Jang (ORCID: https://orcid.org/0000-0002-4689-392X)
- Xuangao Wu (ORCID: https://orcid.org/0000-0002-6293-7363)
- Sunmin Park (ORCID: https://orcid.org/0000-0002-6092-8340)
- Min‐Jung Kim (ORCID: https://orcid.org/0000-0002-2712-9977)
- Ting Zhang (ORCID: https://orcid.org/0000-0003-4839-6297)
- Hye‐Jeong Yang
Institutions
- Hoseo University (KR)
- Korea Food Research Institute (KR)
Publication Details
- Journal
- Nutrients
- Published
- 2024-10-31
- DOI
- https://doi.org/10.3390/nu16213751
- Citations
- 13
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.05
Funders
- Korea Food Research Institute