Water as a Structural Marker in Gelatin Hydrogels with Different Cross-Linking Nature

We have studied the molecular properties of water in physically and chemically cross-linked gelatin hydrogels by FTIR-spectroscopy, NMR relaxation, and diffusivity and broadband dielectric spectroscopy, which are sensitive to dynamical properties of water, being a structural marker of polymer network. All experiments demonstrated definite reinforcement of the hydrogel net structure and an increase in the amount of hydrate water. FTIR experiments have shown that the chemical cross-linking of gelatin molecules initiates an increase in the collagen-like triple helices "strength", as a result of infused restriction on protein molecular mobility. The "strengthening" of protein chains hinders the mobility of protein fragments, introducing complex modifications into the structural properties of water which are remained practically unchanged up to up to 30-40 °C.

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Publication Details

Journal
International Journal of Molecular Sciences
Published
2024-10-31
DOI
https://doi.org/10.3390/ijms252111738
Citations
15
Primary Topic
Collagen: Extraction and Characterization
Type
article
Field-Weighted Citation Impact
2.60

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article

Water as a Structural Marker in Gelatin Hydrogels with Different Cross-Linking Nature

Polina V. Skvortsova, Mariia A. Kazantseva, Svetlana Rostislavovna Derkach, Alena A. Nikiforova et al.
15 citations
International Journal of Molecular Sciences
Collagen: Extraction and Characterization
2.60
article

Water as a Structural Marker in Gelatin Hydrogels with Different Cross-Linking Nature

Polina V. Skvortsova, Mariia A. Kazantseva, Svetlana Rostislavovna Derkach, Alena A. Nikiforova, Yuriy F. Zuev, О. С. Зуева, Liliya R. Bogdanova, Rauf Kurbanov, Mariya A. Klimovitskaya, Ivan V. Lunev
article en
15 citations

Abstract

We have studied the molecular properties of water in physically and chemically cross-linked gelatin hydrogels by FTIR-spectroscopy, NMR relaxation, and diffusivity and broadband dielectric spectroscopy, which are sensitive to dynamical properties of water, being a structural marker of polymer network. All experiments demonstrated definite reinforcement of the hydrogel net structure and an increase in the amount of hydrate water. FTIR experiments have shown that the chemical cross-linking of gelatin molecules initiates an increase in the collagen-like triple helices "strength", as a result of infused restriction on protein molecular mobility. The "strengthening" of protein chains hinders the mobility of protein fragments, introducing complex modifications into the structural properties of water which are remained practically unchanged up to up to 30-40 °C.

International Journal of Molecular SciencesVol. 25(21)
National Research University Higher School of Economics (RU), Kazan Federal University (RU), Kazan Institute of Biochemistry and Biophysics (RU), Murmansk Arctic State University (RU), Kazan State Power Engineering University (RU)
Russian Science Foundation, Russian Academy of Sciences
Clean water and sanitation
Openalex Percentile: Top 10%
Collagen: Extraction and Characterization
2.60
DOIOpen Access PDFOpenAlex
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