Vertical Graphene-Based Electrochemical Biosensor for Detection of Bleomycin

This study is part of an extended investigation into the quantitative detection of therapeutic molecules with antineoplastic properties, specifically focusing on bleomycin. The objective is to minimize adverse effects while maximizing therapeutic effectiveness. We are presenting the results for bleomycin detection, in terms of cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). We are continuing an approach we have recently started, of an electrochemical biosensor based on graphene, which is evidenced to be a revolutionary nanomaterial. The vertical graphene (VG) biosensor exhibited improved sensitivity, faster response, faster occurrence of the chemical reactions, and higher electrode surface conductivity, than the classical gold IDE sensor. The results for bleomycin detection emphasized that a minimum surface modification VG IDE sensor proved to be more efficient than the classical gold IDE sensor.