Exploring the interplay between Porphyromonas gingivalis KGP gingipain, herpes virus MicroRNA-6, and Icp4 transcript in periodontitis: Computational and clinical insights
The identification of miRNA-6 in periodontitis patients and the strong interaction potential between P. gingivalis KGP gingipain and ICP4 transcripts indicate a possible link between bacterial virulence factors and viral latency dynamics in periodontal tissues. These results highlight the complex interplay between oral pathogens, viral microRNAs, and host immune responses in periodontitis.
Authors
- Raghavendra Vamsi Anegundi (ORCID: https://orcid.org/0000-0002-8269-088X)
- Rex Arunraj (ORCID: https://orcid.org/0000-0002-2739-8325)
- Carlos M. Ardila (ORCID: https://orcid.org/0000-0002-3663-1416)
- Anila Neelakandan
- Pradeep Kumar Yadalam (ORCID: https://orcid.org/0000-0002-6653-4123)
Institutions
- SRM Institute of Science and Technology (IN)
- Universidad de Antioquia (CO)
- Saveetha University (IN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1371/journal.pone.0312162
- Citations
- 4
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 1.60