Cost-Effectiveness of Total Neoadjuvant Therapy With Selective Nonoperative Management for Locally Advanced Rectal Cancer: Analysis of Data From the Organ Preservation for Rectal Adenocarcinoma Trial

TNT with selective NOM is cost effective. The cost-effectiveness of CNCT with NOM relative to SOC is dependent on CNCT being made available to a sufficiently large proportion of patients with LARC. Additional analyses are needed to validate these findings from a societal perspective and in the context of other emerging treatment paradigms for LARC.

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Publication Details

Journal
Journal of Clinical Oncology
Published
2024-10-31
DOI
https://doi.org/10.1200/jco.24.00681
Citations
5
Primary Topic
Colorectal Cancer Surgical Treatments
Type
article
Field-Weighted Citation Impact
1.41
Controls
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article

Cost-Effectiveness of Total Neoadjuvant Therapy With Selective Nonoperative Management for Locally Advanced Rectal Cancer: Analysis of Data From the Organ Preservation for Rectal Adenocarcinoma Trial

Julio García‐Aguilar, Andrew Briggs, Maria Widmar, Mason McCain et al.
5 citations
Journal of Clinical Oncology
Colorectal Cancer Surgical Treatments
1.41
article

Cost-Effectiveness of Total Neoadjuvant Therapy With Selective Nonoperative Management for Locally Advanced Rectal Cancer: Analysis of Data From the Organ Preservation for Rectal Adenocarcinoma Trial

Julio García‐Aguilar, Andrew Briggs, Maria Widmar, Mason McCain, Akriti Mishra Meza, Charles A. Ternent
article en
5 citations

Abstract

TNT with selective NOM is cost effective. The cost-effectiveness of CNCT with NOM relative to SOC is dependent on CNCT being made available to a sufficiently large proportion of patients with LARC. Additional analyses are needed to validate these findings from a societal perspective and in the context of other emerging treatment paradigms for LARC.

Journal of Clinical OncologyVol. 43(6)
Creighton University (US), University of Nebraska at Omaha (US), Memorial Sloan Kettering Cancer Center (US), London School of Hygiene & Tropical Medicine (GB), Methodist Hospital (US)
Openalex Percentile: Top 15%
Colorectal Cancer Surgical Treatments
1.41
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