Genetic Signatures: <i>CD44</i> Single-Nucleotide Polymorphisms Affect Cell Surface Expression and Elevate Risk in Head and Neck Squamous Cell Carcinoma
The T allele and homozygous TT genotype of <i>CD44</i> rs13347 SNP were associated with increased susceptibility to HNSCC and decreased proportion of CD44-positive tumor cells, low SI, and reduced IRS.
Authors
- Sadia Minhas (ORCID: https://orcid.org/0000-0001-8463-2539)
- Shah Jahan (ORCID: https://orcid.org/0000-0002-1730-5025)
- Romeeza Tahir (ORCID: https://orcid.org/0000-0002-0878-7720)
- Haseeb Nisar (ORCID: https://orcid.org/0000-0002-1123-430X)
- Nadeem Afzal (ORCID: https://orcid.org/0000-0001-7477-0487)
- Ali Amar (ORCID: https://orcid.org/0000-0002-3240-0741)
- Muhammad Kashif (ORCID: https://orcid.org/0000-0002-1427-8893)
- Faheem Shahzad (ORCID: https://orcid.org/0000-0002-2238-5912)
- Abdul Hanan Nagi
Institutions
- King Fahd University of Petroleum and Minerals (SA)
- Nishtar Medical College and Hospital (PK)
- University of Health Sciences Lahore (PK)
- Farooq Hospital (PK)
- University of Management and Technology (PK)
Publication Details
- Journal
- JCO Global Oncology
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1200/go.24.00084
- Primary Topic
- Proteoglycans and glycosaminoglycans research
- Type
- article
- Field-Weighted Citation Impact
- 0.00