Efficacy of 1.5% levofloxacin otic solution in treating acute otitis externa: A post hoc analysis of ENT103-3001, a multicenter randomized double-blind parallel-group placebo-controlled phase III study in otitis media with persistent otorrhea
The use of 1.5% LVFX otic solution resulted in a significantly higher rate of improvement in inflammatory findings in the external ear canal and bacterial eradication rate, indicating its efficacy. Thus, 1.5% LVFX otic solution may be an effective treatment for chronic suppurative otitis media and acute otitis media, as well as AOE with NTM.
Authors
- Han Matsuda (ORCID: https://orcid.org/0009-0002-7503-0872)
- Kayo Suzuki
- Tetsuo Ikezono (ORCID: https://orcid.org/0000-0002-6929-5084)
- Masafumi Sawada
- Haruo Takahashi
Institutions
- Kyoto University (JP)
- Tokyo-Kita Medical Center (JP)
- Saitama Medical University Hospital (JP)
Publication Details
- Journal
- Auris Nasus Larynx
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1016/j.anl.2024.10.015
- Primary Topic
- Ear Surgery and Otitis Media
- Type
- article
- Field-Weighted Citation Impact
- 0.00