Signet cell carcinoma of the colon in an 11-year-old child: A case report and review of literature

Colon cancer is uncommon in children. This article reports a case of signet ring cell carcinoma in an 11-year-old child who presented with acute intestinal obstruction. An 11-year-old boy presented with progressive abdominal distension associated with constipation. The child underwent an abdominal X-ray in the erect position which revealed dilated bowel loops. Contrast enhanced computed tomography abdomen reported circumferential thickening involving 3.5 cm of the mid-transverse colon. The child underwent exploratory laparotomy which revealed mid transverse colon tumor. Tumor was resected with side-to-side anastomosis. Postoperative histopathology showed signet ring cell carcinoma. He was started on adjuvant chemotherapy. Surgery followed by adjuvant chemotherapy is the modality of treatment colorectal carcinoma. There are no screening guidelines available for the pediatric age group, however early diagnosis through colonoscopy screening can be considered to improve the prognosis.

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Journal
Pediatric Hematology Oncology Journal
Published
2024-10-31
DOI
https://doi.org/10.1016/j.phoj.2024.10.155
Primary Topic
Genetic factors in colorectal cancer
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article
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article

Signet cell carcinoma of the colon in an 11-year-old child: A case report and review of literature

R Lekshmi, Shreyosi Mandal, Sweety Gupta, Satya Sree Balija et al.
Pediatric Hematology Oncology Journal
Genetic factors in colorectal cancer
article

Signet cell carcinoma of the colon in an 11-year-old child: A case report and review of literature

R Lekshmi, Shreyosi Mandal, Sweety Gupta, Satya Sree Balija, Mridul Khanna, Manoj Gupta, Pragya Singh, Ravi Hari Phulware, Rajive Kumar
article en

Abstract

Colon cancer is uncommon in children. This article reports a case of signet ring cell carcinoma in an 11-year-old child who presented with acute intestinal obstruction. An 11-year-old boy presented with progressive abdominal distension associated with constipation. The child underwent an abdominal X-ray in the erect position which revealed dilated bowel loops. Contrast enhanced computed tomography abdomen reported circumferential thickening involving 3.5 cm of the mid-transverse colon. The child underwent exploratory laparotomy which revealed mid transverse colon tumor. Tumor was resected with side-to-side anastomosis. Postoperative histopathology showed signet ring cell carcinoma. He was started on adjuvant chemotherapy. Surgery followed by adjuvant chemotherapy is the modality of treatment colorectal carcinoma. There are no screening guidelines available for the pediatric age group, however early diagnosis through colonoscopy screening can be considered to improve the prognosis.

Pediatric Hematology Oncology JournalVol. 9(4)
All India Institute of Medical Sciences Rishikesh (IN)
Openalex Percentile: Top 69%
Genetic factors in colorectal cancer
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Signet cell carcinoma of the colon in an 11-year-old child: A case report and review of literature — R Lekshmi, Shreyosi Mandal, et al. · Pediatric Hematology Oncology Journal (2024) | TGRS Research Map | TGRS