Incidence and risk factors of ischemic stroke in patients with cancer-associated venous thromboembolism: from the Contemporary Management and Outcomes in Patients With Venous Thromboembolism Registry-2
In this large VTE registry in the direct oral anticoagulant era, the cumulative incidence of ischemic stroke was 4.0% at 1 year and 4.7% at 3 years in patients with CAVTE, and several independent risk factors of ischemic stroke were identified, including pancreatic cancer, ovarian cancer, lung cancer, dyslipidemia, metastasis, higher D-dimer at VTE diagnosis, and younger age.
Authors
- Kiyonori Togi (ORCID: https://orcid.org/0000-0003-1081-3163)
- Kazunori Otsui
- Ryusuke Nishikawa (ORCID: https://orcid.org/0000-0001-5038-1292)
- Shuhei Tsuji (ORCID: https://orcid.org/0000-0002-6297-5642)
- Wataru Shioyama (ORCID: https://orcid.org/0000-0002-4336-749X)
- Ryuki Chatani (ORCID: https://orcid.org/0009-0009-7622-8494)
- Norimichi Koitabashi (ORCID: https://orcid.org/0000-0002-2113-3422)
- Kensuke Takabayashi (ORCID: https://orcid.org/0000-0002-5805-9879)
- Seiichi Hiramori (ORCID: https://orcid.org/0000-0001-5798-1581)
- Shunsuke Usami (ORCID: https://orcid.org/0000-0003-2605-5600)
- Jiro Sakamoto
- Daisuke Sueta (ORCID: https://orcid.org/0000-0003-0960-0339)
- Yugo Yamashita (ORCID: https://orcid.org/0000-0003-2583-1321)
- Hisato Nakai (ORCID: https://orcid.org/0000-0002-8961-007X)
- Toru Takase
- Kazuhisa Kaneda (ORCID: https://orcid.org/0000-0002-4329-5975)
- Tomohiro Dohke
- Moriaki Inoko (ORCID: https://orcid.org/0000-0003-1388-4899)
- Yoshito Ogihara (ORCID: https://orcid.org/0000-0002-6659-4660)
- Nobutaka Ikeda (ORCID: https://orcid.org/0000-0002-1615-3736)
- Yuji Nishimoto (ORCID: https://orcid.org/0000-0003-1996-8540)
- Satoshi Ikeda (ORCID: https://orcid.org/0000-0001-5203-7911)
- Maki Oi
- Takeshi Morimoto (ORCID: https://orcid.org/0000-0002-6844-739X)
- Takuma Takada (ORCID: https://orcid.org/0000-0002-9172-0163)
- Yoshiaki Tsuyuki (ORCID: https://orcid.org/0000-0003-4718-4620)
- Kitae Kim (ORCID: https://orcid.org/0000-0001-5751-5775)
- Koichiro Murata (ORCID: https://orcid.org/0009-0008-9824-6215)
- Tôru Satô (ORCID: https://orcid.org/0000-0003-1992-5786)
- Hiroshi Mabuchi (ORCID: https://orcid.org/0009-0002-4141-2872)
- Yohei Kobayashi (ORCID: https://orcid.org/0000-0002-7925-0963)
- Takeshi Inoue (ORCID: https://orcid.org/0000-0002-4381-8000)
- Kaoru Dohi
- Po‐Min Chen (ORCID: https://orcid.org/0000-0003-1270-2205)
- Takeshi Kimura
- Kosuke Doi
Institutions
- Toho University (JP)
- Hyogo Medical University (JP)
- Shiga University of Medical Science (JP)
- Gunma University (JP)
- Mie University (JP)
- Kyoto University (JP)
- Tenri Hospital (JP)
- Kyoto Medical Center (JP)
- Taoka Hospital (JP)
- Osaka Kaisei Hospital (JP)
- Kurashiki Central Hospital (JP)
- Kobe University Hospital (JP)
- Toho University Ohashi Medical Center (JP)
- Kindai University Hospital (JP)
- Kansai Electric Power Hospital (JP)
- Shimada Municipal Hospital (JP)
- Shizuoka City Hospital (JP)
- Otsu Red Cross Hospital (JP)
- Hyogo Prefectural Amagasaki General Medical Center (JP)
- Tokyo Women's Medical University (JP)
- Koto Hospital (JP)
- Osaka Red Cross Hospital (JP)
- Japanese Red Cross Society Wakayama Medical Center (JP)
- Shiga Medical Center (JP)
- Kitano Hospital (JP)
- Kokura Memorial Hospital (JP)
- Kobe City Medical Center General Hospital (JP)
- Municipal Hirakata City Hospital (JP)
- Nagasaki University (JP)
- Kindai University (JP)
- Kumamoto University (JP)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1016/j.rpth.2024.102617
- Primary Topic
- Venous Thromboembolism Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Society for the Promotion of Science