Impact of sample processing delays on plasma markers of inflammation, chemotaxis, cell death, and blood coagulation
Delayed sample processing for up to 72 hours at either RT or 4°C did not significantly affect cytokines, chemokines, cfDNA, or blood clotting potential in plasma samples from healthy volunteers and ICU patients. A "simplified" biosampling protocol is a feasible solution for conducting biosampling research at hospitals without local processing capacity.
Authors
- Alexandra Binnie (ORCID: https://orcid.org/0000-0003-2969-8177)
- Patricia C. Liaw (ORCID: https://orcid.org/0000-0002-7783-1393)
- Alison Fox‐Robichaud (ORCID: https://orcid.org/0000-0001-9912-3606)
- Jennifer Tsang (ORCID: https://orcid.org/0000-0002-1809-0505)
- Dhruva J. Dwivedi
- Vanessa J. Gyorffy
Institutions
- Niagara Health System (CA)
- William Osler Health System (CA)
- Thrombosis and Atherosclerosis Research Institute (CA)
- McMaster University (CA)
Publication Details
- Journal
- PLoS ONE
- Published
- 2024-10-31
- DOI
- https://doi.org/10.1371/journal.pone.0311921
- Citations
- 5
- Primary Topic
- Blood disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.75