Transcriptomics profiling of the non-small cell lung cancer microenvironment across disease stages reveals dual immune cell-type behaviors
The dual profile of several immune cells, most notably T-cell populations, have been discussed in the context of diseases such as cancer. Here, we report the duality of NK cells which should be taken into account in conjunction with other immune cell populations and behaviors in predicting prognosis, immune response or evasion.
Authors
- Maria Fernanda Senosain
- Anne Pradines (ORCID: https://orcid.org/0000-0002-2449-678X)
- Michael N. Kammer (ORCID: https://orcid.org/0000-0001-7912-8450)
- Myrna Hurtado (ORCID: https://orcid.org/0000-0003-0704-8384)
- Eric Chetaille
- Fabien Maldonado (ORCID: https://orcid.org/0000-0002-6504-2063)
- Leila Khajavi (ORCID: https://orcid.org/0000-0002-4082-4288)
- A. Passioukov
- Olivier Delfour
- Abdelmounim Essabbar (ORCID: https://orcid.org/0000-0003-1942-6805)
- Anne Casanova
- Pierre Launay (ORCID: https://orcid.org/0000-0002-3560-1389)
- Anna Kruczynski
- Julien Mazières (ORCID: https://orcid.org/0000-0002-5921-7613)
- Véra Pancaldi (ORCID: https://orcid.org/0000-0002-7433-624X)
- Estelle Clermont
- Abderrahim Mahfoudi
- Jérôme Besse
- Alexis Coullomb (ORCID: https://orcid.org/0000-0003-3164-6640)
- Francisco Cruzalegui
- Gilles Favre (ORCID: https://orcid.org/0000-0002-2344-1883)
- Shilin Zhao (ORCID: https://orcid.org/0000-0002-3921-3965)
- Yong Zou (ORCID: https://orcid.org/0000-0002-5328-7119)
- Ting Xie (ORCID: https://orcid.org/0000-0002-2585-8578)
- Sandrine Gouin
- Léa Boutillet
- Prosper Burq
Institutions
- Centre National de la Recherche Scientifique (FR)
- Université Toulouse III - Paul Sabatier (FR)
- Inserm (FR)
- Université Fédérale de Toulouse Midi-Pyrénées (FR)
- Barcelona Supercomputing Center (ES)
- Centre Hospitalier Universitaire de Toulouse (FR)
- Centre de Recherches en Cancérologie de Toulouse (FR)
- Hôpital Larrey (FR)
- Institut Claudius Regaud (FR)
- Pierre Fabre (France) (FR)
- Vanderbilt University Medical Center (US)
- Universitat Politècnica de Catalunya (ES)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-10-31
- DOI
- https://doi.org/10.3389/fimmu.2024.1394965
- Citations
- 3
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.72