Liraglutide Ameliorates Renal Endothelial Dysfunction in Diabetic Rats Through the Inhibition of the Dll4/Notch2 Pathway
The findings indicate that Liraglutide has a substantial effect on decreasing urinary protein excretion and improving vascular microinflammation, thus alleviating endothelial dysfunction in diabetic nephropathy. This observed mechanism can be attributed to the inhibition of the Dll4/Notch2 signaling pathway.
Authors
- Yan Pan (ORCID: https://orcid.org/0009-0006-3445-8265)
- Hui Zhang
- Weidong Chen (ORCID: https://orcid.org/0000-0002-7787-2638)
- Yulin Chen (ORCID: https://orcid.org/0000-0001-9710-4436)
- Yining Li (ORCID: https://orcid.org/0009-0004-4017-9479)
Institutions
- Bengbu Medical College (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
Publication Details
- Journal
- Diabetes Metabolic Syndrome and Obesity
- Published
- 2024-10-01
- DOI
- https://doi.org/10.2147/dmso.s492252
- Citations
- 3
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.07