A retrospective study on ABO Blood Groups and Chronic Obstructive Pulmonary Diseases.

Objective: To investigate the potential association between ABO blood groups and the incidence of chronic obstructive pulmonary disease (COPD) in a population from Hyderabad, Pakistan.Methodology: This was a retrospective comparative type of study conducted in the pulmonology OPD (Out Patient Department) of the Liaquat University Hospital Hyderabad from June 2023 to September 2023. Five hundred and thirty (n =530) patients who visited pulmonology OPD were selected. Three hundred male and 230 female patients who visited the Pulmonology OPD for different respiratory illnesses were included in this study. COPD was diagnosed by the historyof illness and x-ray chest posterior-anterior (P/A) view. Blood groups were determined by the blood agglutination method.Results: The results show that most COPD male patients (13.20%) contain the O group, 8.45% have the A group, 5.66% have the B group, and 0.56% have the AB group. The P value was > 0.05, which was relatively higher in the O group patient when Fischer’s exact test was applied.Conclusion: The study concludes that there was a potential association between ABO blood group O and an increased risk of chronic obstructive pulmonary disease (COPD), warranting further research to confirm these findings. Key words: Blood group, chronic obstructive pulmonary disease, Rhesus group, Hyderabad, Pakistan.