Reply to Comment on Ou Y, et al. “UBA2 as a Prognostic Biomarker and Potential Therapeutic Target in Glioma”. Frontiers in Bioscience-Landmark. 2024; 29: 144
Thanks very much for the comments [1].Satisfying the proportional hazards (PH) assumption improves the interpretability of the Cox regression model, but is not necessary [2].In fact, the PH assumption is difficult to realise in medical research.This has been discussed at length by authoritative epidemiologists [3].We fully agree with several of the improvements recommended by the commenters, which would certainly make the results more stable and reliable.We are not opposed to conducting PH assumption tests, but the results will not be affected by this.
Authors
- Tianqi Du (ORCID: https://orcid.org/0000-0002-1894-9607)
- Qiuning Zhang (ORCID: https://orcid.org/0000-0001-9476-1537)
- Meng Dong (ORCID: https://orcid.org/0000-0002-4209-3781)
- Junru Chen (ORCID: https://orcid.org/0000-0003-4553-6979)
- Yuhong Ou
- Yuhang Wang (ORCID: https://orcid.org/0000-0002-0188-160X)
- Dandan Wang (ORCID: https://orcid.org/0000-0001-8643-2514)
- Xiaohu Wang (ORCID: https://orcid.org/0009-0005-0876-3680)
- Hongtao Luo (ORCID: https://orcid.org/0000-0002-2191-4552)
- Zhen Yang
- Ruifeng Liu
Institutions
- Chinese Academy of Sciences (CN)
- Gansu University of Traditional Chinese Medicine (CN)
- Institute of Modern Physics (CN)
- University of Chinese Academy of Sciences (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2024-10-14
- DOI
- https://doi.org/10.31083/j.fbl2910354
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00