Thyroid Dysfunction In Metabolic Syndrome In Patients: An Observational Study

Objective: To assess the clinico-demographic profile thyroid dysfunction (TD in patients with metabolic syndrome (MetS). Methods: Research was done at the Medical Department. We included 200 MetS patients in this investigation. Demographics, anthropometric measurements, significant medical (including FPG, serum TG, and HDL-C values from patients' medical records) and surgical history, family history, lifestyle parameters, history of obesogenic medicine use, vital signs, and physical examination details were collected in case report forms at the screening visit. Results: We included 200 MetS patients in this investigation. The baseline demographics of these patients are presented. Of the recruited patients, 60 (30%) had TD, with women being more likely than males. Overt hypothyroidism was detected in 36 of 200 MetS patients and hyperthyroidism in 4. High waist circumference, lowered HDL-C, elevated HOMA-IR, systolic and diastolic blood pressure, fasting hyperglycemia, and TG were seen in TD patients in this research. More women than men had waist circumferences exceeding 80 cm. Conclusion: Metabolic syndrome complications include thyroid problems. High frequency of TD in MetS patients suggests a thyroid-MetS interaction. This investigation will help link TD and MetS in Indian patients. Early identification of TD in MetS may help change disease course with lifestyle modifications.