Managing Pheochromocytoma And Paraganglioma In Pregnancy: Lessons From A Clinical Case

Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors that produce excessive catecholamines, posing significant risks during pregnancy. This case study follows a 24-year-old woman with untreated hypertension and Ménard’s triad symptoms, initially managed without detailed investigation. Elevated plasma metanephrine levels and imaging confirmed a pheochromocytoma, and though the patient was lost to follow-up for a year, she was readmitted at 13 weeks of gestation. A pre-pregnancy CT scan identified a large hypervascular left adrenal mass. Following normal genetic testing and a multidisciplinary approach, she underwent a successful laparotomy with left adrenalectomy, with no complications in the ongoing pregnancy. This case underscores the importance of early diagnosis and appropriate management of PPGLs to prevent adverse maternal and fetal outcomes, highlighting the need for careful monitoring and surgical intervention when necessary