An unusually encountered folliculosebaceous cystic hamartoma clinically resembling an epidermal inclusion cyst

Folliculosebaceous cystic hamartoma (FSCH) is a rare cutaneous hamartoma comprising epithelial and mesenchymal components. It typically appears as slow-growing, skin-coloured nodules on the face and scalp. We report a case of a mid-forties male with a 4 mm nodule on his left temple, initially thought to clinically represent an epidermal inclusion cyst (EIC). Excisional biopsy results identified the lesion as FSCH, characterised by its unique dilated infundibulocystic configuration with radiating sebaceous lobules and associated mesenchymal elements. FSCH can be misdiagnosed for EIC due to similar clinical presentations but has distinct histological features. Surgical excision is the standard treatment, and the patient has remained recurrence-free since the procedure. This case underscores the importance of considering FSCH in the differential diagnosis of particularly facial and scalp nodules.

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Publication Details

Journal
BMJ Case Reports
Published
2024-10-01
DOI
https://doi.org/10.1136/bcr-2024-261830
Primary Topic
Cancer and Skin Lesions
Type
article
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article

An unusually encountered folliculosebaceous cystic hamartoma clinically resembling an epidermal inclusion cyst

John Trinidad, Dimitra Pouli, Sophia Neman, Jordan T. Said
BMJ Case Reports
Cancer and Skin Lesions
article

An unusually encountered folliculosebaceous cystic hamartoma clinically resembling an epidermal inclusion cyst

John Trinidad, Dimitra Pouli, Sophia Neman, Jordan T. Said
article en

Abstract

Folliculosebaceous cystic hamartoma (FSCH) is a rare cutaneous hamartoma comprising epithelial and mesenchymal components. It typically appears as slow-growing, skin-coloured nodules on the face and scalp. We report a case of a mid-forties male with a 4 mm nodule on his left temple, initially thought to clinically represent an epidermal inclusion cyst (EIC). Excisional biopsy results identified the lesion as FSCH, characterised by its unique dilated infundibulocystic configuration with radiating sebaceous lobules and associated mesenchymal elements. FSCH can be misdiagnosed for EIC due to similar clinical presentations but has distinct histological features. Surgical excision is the standard treatment, and the patient has remained recurrence-free since the procedure. This case underscores the importance of considering FSCH in the differential diagnosis of particularly facial and scalp nodules.

BMJ Case ReportsVol. 17(10)
Brigham and Women's Hospital (US), Boston Children's Hospital (US), Harvard University (US), Medical College of Wisconsin (US), Massachusetts General Hospital (US)
Openalex Percentile: Top 60%
Cancer and Skin Lesions
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An unusually encountered folliculosebaceous cystic hamartoma clinically resembling an epidermal inclusion cyst — John Trinidad, Dimitra Pouli, et al. · BMJ Case Reports (2024) | TGRS Research Map | TGRS