Evaluation of the sedative properties of oral trazodone, gabapentin or their combination in healthy cats

Administration of oral trazodone alone at 5 mg/kg or in combination with gabapentin at 10 mg/kg resulted in significant sedation in healthy cats with no evident side effects. The degree of sedation was more profound when both drugs were combined, but a gabapentin dose of 10 mg/kg alone failed to provide significant sedation in this population.

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Publication Details

Journal
Journal of Feline Medicine and Surgery
Published
2024-10-01
DOI
https://doi.org/10.1177/1098612x241281481
Citations
6
Primary Topic
Veterinary Pharmacology and Anesthesia
Type
article
Field-Weighted Citation Impact
3.83

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article

Evaluation of the sedative properties of oral trazodone, gabapentin or their combination in healthy cats

Ron J. Johnson, Andrew Downie, Gabrielle Monteith, Laura Tucker et al.
6 citations
Journal of Feline Medicine and Surgery
Veterinary Pharmacology and Anesthesia
3.83
article

Evaluation of the sedative properties of oral trazodone, gabapentin or their combination in healthy cats

Ron J. Johnson, Andrew Downie, Gabrielle Monteith, Laura Tucker, Alexander Valverde, Shauna L. Blois, Andrea Sánchez, Yu Gu, Pamela Longworth
article en
6 citations

Abstract

Administration of oral trazodone alone at 5 mg/kg or in combination with gabapentin at 10 mg/kg resulted in significant sedation in healthy cats with no evident side effects. The degree of sedation was more profound when both drugs were combined, but a gabapentin dose of 10 mg/kg alone failed to provide significant sedation in this population.

Journal of Feline Medicine and SurgeryVol. 26(10)
University of Guelph (CA)
OVC Pet Trust
Good health and well-being
Openalex Percentile: Top 7%
Veterinary Pharmacology and Anesthesia
3.83
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