Cuproptosis-related signature predicts prognosis and indicates tumor immune infiltration in bladder cancer
Our study sheds light on the biological functions of CPRGs within the TME of BLCA and their correlations with clinical parameters and patient prognosis. The identification of distinct molecular clusters with varying prognoses and immune cell infiltrations highlights the heterogeneity of BLCA and underscores the potential of CPRGs as biomarkers for prognosis and therapeutic targets. These findings offer new perspectives for the development of immunotherapeutic strategies in the treatment of BLCA patients, potentially leading to more personalized and effective cancer therapies.
Authors
- Damian Kołat (ORCID: https://orcid.org/0000-0002-1086-3796)
- Dingwei Ye (ORCID: https://orcid.org/0000-0001-7770-9753)
- Haoyue Sheng (ORCID: https://orcid.org/0000-0002-1707-6621)
- Jianhua Gu (ORCID: https://orcid.org/0000-0002-1578-6814)
- Lihua Yan (ORCID: https://orcid.org/0000-0003-4271-6317)
- Guo-Hai Shi
- Yongqiang Huang
Institutions
- Shanghai Medical College of Fudan University (CN)
- Fudan University Shanghai Cancer Center (CN)
- Medical University of Lodz (PL)
Publication Details
- Journal
- Translational Andrology and Urology
- Published
- 2024-10-01
- DOI
- https://doi.org/10.21037/tau-24-456
- Citations
- 1
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.57