Serum from Hypertensive Patients Induces Cancer-Supporting Phenotype of Vascular Endothelium In Vitro
Our report shows that hypertension may potentiate cancer cell aggressiveness by modulating endothelial cell phenotype. Further tests with antihypertensive drugs are required to assess whether effective treatment of hypertension can mitigate its cancer-promoting potential.
Authors
- Andrzej Tykarski (ORCID: https://orcid.org/0000-0001-9786-6334)
- Justyna Mikuła‐Pietrasik (ORCID: https://orcid.org/0000-0002-8267-5428)
- Paweł Uruski (ORCID: https://orcid.org/0000-0002-6798-3043)
- Krzysztof Książek (ORCID: https://orcid.org/0000-0002-6066-5747)
Institutions
- Poznan University of Medical Sciences (PL)
- Heliodor Swiecicki Clinical Hospital (PL)
Publication Details
- Journal
- Biomolecules
- Published
- 2024-10-28
- DOI
- https://doi.org/10.3390/biom14111374
- Citations
- 4
- Primary Topic
- Angiogenesis and VEGF in Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Narodowym Centrum Nauki