Serum Albumin and Interleukin 6 Levels as Risk Factors of Morbidity and Mortality in Burn Patients

Background: Interleukin-6 (IL-6) is a major player in setting off this cascade of inflammatory responses. The loss of plasma proteins like albumin and a decrease in plasma colloid osmotic pressure led to increased fluid leakage from blood capillaries into normal tissue and the lungs. Objectives: The objective of this investigation was to evaluate serum albumin and IL-6 level as risk factors of morbidity and mortality in burn patients. Methods: The prospective cohort investigation was conducted on 25 burn patients aged from 8 to 70 years, both sexes, with second, or third-degree burn, scald or a flame burn if the surface area is >15%. IL-6 and serum albumin were measured at first, third and seventh days in all patients. Results: The body surface burned and abbreviated burn severity index (ABSI) were significantly increased in non-survivors than survivors (P