Unveiling the diagnostic potential: hypocalcemia, eosinopenia, and hypochloremia as clinical predictors for leptospirosis

Background. Leptospirosis presents diagnostic challenges due to its nonspecific symptoms which often overlap with other febrile illnesses. Identifying reliable clinical predictors could streamline diagnostic processes and improve patient outcomes. Methods. This study analyzed the occurrence of hypocalcemia, eosinopenia, and hypochloremia in 200 patients suspected of having leptospirosis. We conducted a retrospective analysis comparing laboratory values of confirmed leptospirosis cases against those of patients where the disease was ruled out. Results. Preliminary results indicate significant correlations between the presence of these three clinical markers and confirmed cases of leptospirosis. Conclusion. Hypocalcemia, eosinopenia, and hypochloremia show potential as clinical predictors for leptospirosis, suggesting that these markers could be integrated into diagnostic protocols to enhance early detection and treatment strategies.