Successfully intravenous thrombolytic therapy in systemic lupus erythematosus-related ischemic stroke: A case report

After thrombolysis, the NIHSS score of the patient decreased to zero. The computed tomography scan was reexamined 24 hours later, and no acute changes or hemorrhage were identified in the infarcted area. Subsequent imaging and serological analyses indicated that HR-MRI of the responsible vessel was negative, but the infarction in this patient was still regarded as being caused by vasculitis of the right posterior cerebral artery in the region supplying the thalamus. This is the first case of successful intravenous thrombolytic therapy with rt-PA in a patient with SLE secondary to stroke with an NIHSS score of 3. This provides further evidence for expanding the reference of indications with rt-PA intravenous thrombolysis.

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Publication Details

Journal
Medicine
Published
2024-10-25
DOI
https://doi.org/10.1097/md.0000000000040203
Primary Topic
Systemic Lupus Erythematosus Research
Type
article
Field-Weighted Citation Impact
0.00

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article

Successfully intravenous thrombolytic therapy in systemic lupus erythematosus-related ischemic stroke: A case report

Hong-Jian Guan, Guanglin Liu, Yong Wang
Medicine
Systemic Lupus Erythematosus Research
article

Successfully intravenous thrombolytic therapy in systemic lupus erythematosus-related ischemic stroke: A case report

Hong-Jian Guan, Guanglin Liu, Yong Wang
article en

Abstract

After thrombolysis, the NIHSS score of the patient decreased to zero. The computed tomography scan was reexamined 24 hours later, and no acute changes or hemorrhage were identified in the infarcted area. Subsequent imaging and serological analyses indicated that HR-MRI of the responsible vessel was negative, but the infarction in this patient was still regarded as being caused by vasculitis of the right posterior cerebral artery in the region supplying the thalamus. This is the first case of successful intravenous thrombolytic therapy with rt-PA in a patient with SLE secondary to stroke with an NIHSS score of 3. This provides further evidence for expanding the reference of indications with rt-PA intravenous thrombolysis.

MedicineVol. 103(43)
Yanbian University (CN), Yanbian University Hospital (CN)
Natural Science Foundation of Jilin Province, People's Government of Jilin Province, Yanbian University
Good health and well-being
Openalex Percentile: Top 67%
Systemic Lupus Erythematosus Research
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