A Case of Syphilis With Ocular Involvement: Persistent Negative Serology in a Patient With Multiple Sclerosis
Diagnostic algorithms for syphilis are based on serology. However, with the advent of immunosuppressive therapies, these algorithms may fail. We report a case of an individual with multiple sclerosis on treatment with ofatumumab and secondary syphilis with visual and auditory systems involvement and persistent negative treponemal and nontreponemal tests.
Authors
- Ευδοκία Μανδαλά
- Andrea Cicero
- Luca Pipitò (ORCID: https://orcid.org/0000-0002-1871-4285)
- Cinzia Calà (ORCID: https://orcid.org/0000-0001-5776-0121)
- Antonio Cascio (ORCID: https://orcid.org/0000-0002-1992-1796)
- Paola Di Carlo (ORCID: https://orcid.org/0000-0003-4418-5855)
- Alice Annalisa Medaglia (ORCID: https://orcid.org/0000-0001-5074-070X)
- Irene Ganci
- Simona D’Avenia
Institutions
- Check Point (Israel) (IL)
- Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo (IT)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2024-09-27
- DOI
- https://doi.org/10.1093/ofid/ofae563
- Citations
- 2
- Primary Topic
- Syphilis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.65