Association of mid-regional pro-adrenomedullin with office and 24-h ambulatory blood pressure in a Swiss general population sample
The cross-sectional negative association of MR-proADM with DBP is in line with known vasodilatory properties of ADM. The positive association between MR-proADM and nighttime SBP at baseline may reflect endothelial dysfunction believed to be part of the pathogenesis of nocturnal hypertension. The association of higher baseline MR-proADM levels with increased SBP and PP at 3-year follow-up suggests that ADM levels could be a marker of cardiovascular risk.
Authors
- Belén Ponte (ORCID: https://orcid.org/0000-0003-4730-6050)
- Menno T Pruijm (ORCID: https://orcid.org/0000-0003-1027-1851)
- Bruno Vogt (ORCID: https://orcid.org/0000-0002-1548-6387)
- Michel Burnier (ORCID: https://orcid.org/0000-0003-1283-8487)
- Murielle Bochud (ORCID: https://orcid.org/0000-0002-5727-0218)
- Daniel Ackermann (ORCID: https://orcid.org/0000-0003-0550-354X)
- John J. Baldwin
Institutions
- University of Bern (CH)
- University Hospital of Bern (CH)
- Centre Hospitalier Universitaire Vaudois (CH)
- University Hospital of Geneva (CH)
- Centre universitaire de médecine générale et santé publique, Lausanne (CH)
- University of Lausanne (CH)
Publication Details
- Journal
- Journal of Hypertension
- Published
- 2024-09-18
- DOI
- https://doi.org/10.1097/hjh.0000000000003866
- Citations
- 1
- Primary Topic
- Neuropeptides and Animal Physiology
- Type
- article
- Field-Weighted Citation Impact
- 0.27
Funders
- National Science Foundation
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung