Sleep and circadian rhythm disturbances as risk and progression factors for multiple chronic overlapping pain conditions: a protocol for a longitudinal study
This research aims to (1) comprehensively characterize sleep/circadian disturbances in individuals with single and multiple COPCs using multimodal in-home assessments; (2) examine the associations between sleep/circadian disturbances, changes in pain amplification, and psychological distress; and (3) investigate the relationship among these factors and the progression in the number of pain sites, a proxy for multiple COPCs. The findings will provide insights into the mechanisms leading to multiple COPCs, potentially informing treatment and prevention strategies for these complex conditions.
Authors
- Megan E. Petrov (ORCID: https://orcid.org/0000-0001-5443-7548)
- Aram S. Mardian (ORCID: https://orcid.org/0000-0001-6920-8537)
- Shawn D. Youngstedt
- Jeffrey A. Elliott (ORCID: https://orcid.org/0000-0002-3639-0309)
- Kit K. Elam (ORCID: https://orcid.org/0000-0003-0319-5897)
- Frank LoVecchio (ORCID: https://orcid.org/0000-0002-2920-9073)
- Surabhi Sajith
- Nina Winsick
- Kate Alperin (ORCID: https://orcid.org/0009-0003-2292-5813)
- Keenan A. Pituch (ORCID: https://orcid.org/0000-0003-0768-6490)
- Steven Z. George (ORCID: https://orcid.org/0000-0003-4988-9421)
- Chung Jung Mun (ORCID: https://orcid.org/0000-0002-2439-8100)
- Mary C. Davis (ORCID: https://orcid.org/0000-0002-3226-4516)
- Matthew J. Reid (ORCID: https://orcid.org/0000-0001-7270-243X)
- Roger Benton Fillingim (ORCID: https://orcid.org/0000-0002-7699-8183)
- Ananya Lakhotia
- Ryan Eckert
- K.J. Kohler
Institutions
- University of Arizona (US)
- Johns Hopkins University (US)
- Duke University (US)
- Johns Hopkins Medicine (US)
- University of Florida (US)
- University of California San Diego (US)
- Clinical Research Institute (US)
- Valley Medical Center (US)
- Phoenix VA Health Care System (US)
- Indiana University Bloomington (US)
- HonorHealth (US)
- Circadian (United States) (US)
- Arizona State University (US)
Publication Details
- Journal
- PAIN Reports
- Published
- 2024-10-24
- DOI
- https://doi.org/10.1097/pr9.0000000000001194
- Citations
- 3
- Primary Topic
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Arizona State University
- National Institute of Neurological Disorders and Stroke