Tobacco Smoking Functional Networks: A Whole-Brain Connectome Analysis in 24 539 Individuals
This study identifies rsFC subnetworks related to chronic nicotine use through whole-brain connectome analysis. The findings confirm that widespread alterations in rsFC are centered around hub nodes within the basal ganglia, including bilateral nucleus accumbens, putamen, caudate, and globus pallidus. In addition, our analysis found a clique-forming subnetwork vulnerable to tobacco smoking consisting of regions from the visual, dorsal/ventral attention, and frontoparietal networks.
Authors
- Peter Kochunov (ORCID: https://orcid.org/0000-0003-3656-4281)
- Luba Yammine (ORCID: https://orcid.org/0000-0001-5639-8802)
- Hwiyoung Lee (ORCID: https://orcid.org/0000-0002-3855-2316)
- Tianzhou Ma (ORCID: https://orcid.org/0000-0003-3605-0811)
- Zhenyao Ye (ORCID: https://orcid.org/0000-0002-6530-1088)
- Shuo Chen (ORCID: https://orcid.org/0000-0002-7990-4947)
- L. Elliot Hong (ORCID: https://orcid.org/0000-0002-1472-2659)
- Jiaao Yu (ORCID: https://orcid.org/0000-0002-4665-200X)
- Yezhi Pan (ORCID: https://orcid.org/0009-0001-4014-0302)
- Chuan Bi
Institutions
- University of Maryland, Baltimore (US)
- Foundation for the National Institutes of Health (US)
- University of Maryland, College Park (US)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- Nicotine & Tobacco Research
- Published
- 2024-10-28
- DOI
- https://doi.org/10.1093/ntr/ntae256
- Citations
- 2
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.69