Chemotherapy-induced increase in CD47 expression in epithelial ovarian cancer
CD47 is highly expressed in ovarian cancer, and NACT increases the expression of CD47, which may contribute to tumor immune evasion. It is possible that platinum-based chemotherapy may result in elevated <i>CD47</i> mRNA expression and cell surface CD47 protein expression.
Authors
- Jinghe Lang
- Xueqin Wang (ORCID: https://orcid.org/0000-0001-5205-9950)
- Ling Zhao (ORCID: https://orcid.org/0000-0002-0811-3160)
- Haining Liu (ORCID: https://orcid.org/0000-0002-1649-2316)
Institutions
- Qingdao University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Qingdao Municipal Hospital (CN)
Publication Details
- Journal
- Gland Surgery
- Published
- 2024-10-01
- DOI
- https://doi.org/10.21037/gs-24-400
- Citations
- 2
- Primary Topic
- Phagocytosis and Immune Regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.48
Funders
- Massachusetts Department of Agricultural Resources
- Peking Union Medical College Hospital