IFN-treated macrophage-derived exosomes prevents HBV-HCC migration and invasion via regulating miR-106b-3p/PCGF3/PI3K/AKT signaling axis
IFN-α-induced macrophage-derived miR-106b-3p inhibits HBV replication, HBV- Huh7 cells migration and invasion via regulating PCGF3/PI3K/AKT signaling axis. miR-106b-3p and PCGF3 were potential biomarkers in the prevention and treatment of HBV-HCC.
Authors
- Chaohui Chen (ORCID: https://orcid.org/0000-0002-6968-715X)
- Xiaoqing Tan (ORCID: https://orcid.org/0000-0002-3303-2493)
- Tao Zhang (ORCID: https://orcid.org/0000-0003-2860-8731)
- Qi Yin (ORCID: https://orcid.org/0000-0002-6392-9736)
- Tao Shen (ORCID: https://orcid.org/0009-0009-3463-8567)
- Liang Yu (ORCID: https://orcid.org/0009-0007-3922-3454)
- Shiheng Xu
- Jing Chen (ORCID: https://orcid.org/0000-0003-1099-3766)
- Li Li
Institutions
- Kunming University of Science and Technology (CN)
- First People's Hospital of Yunnan Province (CN)
- Innovation Team (China) (HK)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2024-10-28
- DOI
- https://doi.org/10.3389/fcimb.2024.1421195
- Citations
- 5
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- National Natural Science Foundation of China
- Yunnan Provincial Science and Technology Department