Commentator Discussion: Heart transplant survival and the use of donors with intracranial bleeding: United Network for Organ Sharing registry propensity-matched analysis

Meyer and colleagues are to be congratulated on this large analysis of United Network for Organ Sharing (UNOS) registry recipients in the predonation after cardiac death era.I have 3 questions, one donor-related, one recipientrelated, and one general.As you so convincingly presented, there have been several studies that have addressed this question in the past, and so we know that intracranial bleed heart donors are typically older, more often female, smokers, diabetic, and hypertensive, and your study uses propensity matching to adjust for a number of important factors, but among these, really only donor age is included as far as the donor factors.Are the others not important?And why does just adjusting for age remove the adverse effect of donor intracranial bleed on long-term outcome?

Publication Details

Journal
JTCVS Open
Published
2024-10-28
DOI
https://doi.org/10.1016/j.xjon.2024.10.017
Primary Topic
Transplantation: Methods and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Commentator Discussion: Heart transplant survival and the use of donors with intracranial bleeding: United Network for Organ Sharing registry propensity-matched analysis

JTCVS Open
Transplantation: Methods and Outcomes
article

Commentator Discussion: Heart transplant survival and the use of donors with intracranial bleeding: United Network for Organ Sharing registry propensity-matched analysis

article en

Abstract

Meyer and colleagues are to be congratulated on this large analysis of United Network for Organ Sharing (UNOS) registry recipients in the predonation after cardiac death era.I have 3 questions, one donor-related, one recipientrelated, and one general.As you so convincingly presented, there have been several studies that have addressed this question in the past, and so we know that intracranial bleed heart donors are typically older, more often female, smokers, diabetic, and hypertensive, and your study uses propensity matching to adjust for a number of important factors, but among these, really only donor age is included as far as the donor factors.Are the others not important?And why does just adjusting for age remove the adverse effect of donor intracranial bleed on long-term outcome?

JTCVS OpenVol. 22
Zero hunger
Openalex Percentile: Top 64%
Transplantation: Methods and Outcomes
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Commentator Discussion: Heart transplant survival and the use of donors with intracranial bleeding: United Network for Organ Sharing registry propensity-matched analysis · JTCVS Open (2024) | TGRS Research Map | TGRS