Integrated analysis of multi-omics data for the discovery of biomarkers and therapeutic targets for juvenile idiopathic arthritis
This study employed MR analysis to reveal causal relationships between plasma proteins and JIA, identifying five potential candidate proteins as promising drug targets for JIA, particularly focusing on GP1BA and TNFSF11.
Authors
- Xiaoli Chen (ORCID: https://orcid.org/0000-0001-7327-4860)
- Danying Zheng (ORCID: https://orcid.org/0000-0003-1315-7130)
- Xiufeng Huang (ORCID: https://orcid.org/0000-0002-0861-4045)
- Yixin Cai
- Yung‐Cheng Huang (ORCID: https://orcid.org/0000-0001-5609-9765)
- Zhixun Bai
Institutions
- Wenzhou Medical University (CN)
- Wenzhou Hospital of Traditional Chinese Medicine (CN)
- Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
Publication Details
- Journal
- Journal of Translational Autoimmunity
- Published
- 2024-10-28
- DOI
- https://doi.org/10.1016/j.jtauto.2024.100256
- Citations
- 1
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.45
Funders
- National Natural Science Foundation of China
- Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
- Medical Science and Technology Project of Zhejiang Province
- Natural Science Foundation of Zhejiang Province
- Science and Technology Program of Zhejiang Province